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1

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

Matsumoto, Tomoya, Rauskolb, Stefanie, Polack, Martin, Klose, Johannes, Kolbeck, Roland, Korte, Martin, Barde, Yves-Alain

Journal:

Nature Neuroscience

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

2

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease

Geoffrey L. Stephens, Bonnie Swerdlow, Ebony Benjamin, Anthony J. Coyle, Alison Humbles, Roland Kolbeck, Michael Fung

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 509 KB

english, 2011

3

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

Laviolette, Michel, Gossage, David L., Gauvreau, Gail, Leigh, Richard, Olivenstein, Ron, Katial, Rohit, Busse, William W., Wenzel, Sally, Wu, Yanping, Datta, Vivekananda, Kolbeck, Roland, Molfino, Nes

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 2.21 MB

english, 2013

4

The Role of IgE in Autoimmunity

Sanjuan, Miguel A., Sagar, Divya, Kolbeck, Roland

Journal:

Journal of Allergy and Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 859 KB

english, 2016

5

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Kolbeck, Roland, Kozhich, Alexander, Koike, Masamichi, Peng, Li, Andersson, Cecilia K., Damschroder, Melissa M., Reed, Jennifer L., Woods, Robert, Dall'Acqua, William W., Stephens, Geoffrey L., Erjefa

Journal:

Journal of Allergy and Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

6

Evaluation of ultra-low input RNA sequencing for the study of human T cell transcriptome

Wang, Jingya, Rieder, Sadiye Amcaoglu, Wu, Jincheng, Hayes, Susana, Halpin, Rebecca A., de los Reyes, Melissa, Shrestha, Yashaswi, Kolbeck, Roland, Raja, Rajiv

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 5.92 MB

english, 2019

7

IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression

Wang, Yaya, Mumm, John Brian, Herbst, Ronald, Kolbeck, Roland, Wang, Yue

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

8

Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

Jogdand, Prajakta, Siddhuraj, Premkumar, Mori, Michiko, Sanden, Caroline, JÃ¶nsson, Jimmie, Walls, Andrew F., Kearley, Jennifer, Humbles, Alison A., Kolbeck, Roland, Bjermer, Leif, Newbold, Paul, Erje

Journal:

European Respiratory Journal

Year:

2020

File:

PDF, 3.35 MB

2020

9

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A32. SMOKE-RELATED ALTERATIONS IN LUNG BIOLOGY - CXCR2 Ligands Drive Exacerbated Cellular Inflammation In A Bacterial Exacerbation Model Of Cigarette Smoke-Induced Inflammation

Nikota, Jake K., Shen, Pamela, Morissette, Mathieu, Bauer, Carla, Lambert, Kristen, Kolbeck, Roland, Finch, Donna, Humbles, Alison A., Stampfli, Martin R.

Year:

2012

Language:

english

File:

PDF, 17 KB

english, 2012

10

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] B34. MECHANISMS OF LUNG RESPONSES TO ENVIRONMENTAL TOXINS - BRP-39 But Not AMCase Is Increased In Murine Models Of Cigarette Smoke Exposure

Nikota, James K., Botelho, Fernando M., Bauer, Carla M., Trimble, Nancy J., Kianpour, Sussan, Humbles, Alison A., Kolbeck, Roland, Coyle, Anthony J., StÃ¤mpfli, Martin R.

Year:

2010

File:

PDF, 17 KB

2010

11

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D22. PATHOGENESIS OF LUNG FIBROSIS AND AIRWAY REMODELING - MMP-12 Is A Critical Mediator Of Inflammation, IL-13 Expression And Fibrosis Following Activation Of Fas In The Airways

Kearley, Jennifer, Rebelatto, Marlon, Kolbeck, Roland, Humbles, Alison

Year:

2012

Language:

english

File:

PDF, 18 KB

english, 2012

12

Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

Sawai, Catherine M., Serpas, Lee, Neto, Antonio Galvao, Jang, Geunhyo, Rashidfarrokhi, Ali, Kolbeck, Roland, Sanjuan, Miguel A., Reizis, Boris, Sisirak, Vanja

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 14.81 MB

english, 2018

13

Microbiota Regulates Eosinophils In The Small Intestine

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Journal of Allergy and Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

14

MEDI-551 Treatment Effectively Depletes B Cells and Reduces Serum Titers of Autoantibodies in Mice Transgenic for Sle1 and Human CD19

Gallagher, Sandra, Yusuf, Isharat, McCaughtry, Tom M., Turman, Sean, Sun, Hong, Kolbeck, Roland, Herbst, Ronald, Wang, Yue

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 572 KB

english, 2016

15

Monoclonal Antibody Therapy for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease with Eosinophilic Inflammation

Nixon, John, Newbold, Paul, Mustelin, Tomas, Anderson, Gary P., Kolbeck, Roland

Journal:

Pharmacology & Therapeutics

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

16

Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis

James R. Tonra, Brita S. Reiseter, Roland Kolbeck, Kumiko Nagashima, Robbie Robertson, Bruce Keyt, Ronald M. Lindsay

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 551 KB

english, 2001

17

Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways

An, Ling-Ling, Gorman, Jacob V., Stephens, Geoffrey, Swerdlow, Bonnie, Warrener, Paul, Bonnell, Jessica, Mustelin, Tomas, Fung, Michael, Kolbeck, Roland

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 751 KB

english, 2016

18

Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

Ettinger, Rachel, Karnell, Jodi L., Henault, Jill, Panda, Santosh K., Riggs, Jeffrey M., Kolbeck, Roland, Sanjuan, Miguel A.

Journal:

Year:

2017

Language:

english

File:

PDF, 4.62 MB

english, 2017

19

Brain-Derived Neurotrophic Factor Levels in the Nervous System of Wild-Type and Neurotrophin Gene Mutant Mice

Roland Kolbeck, Ilse Bartke, Walter Eberle, Yves-Alain Barde

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 1021 KB

english, 1999

20

In England Now

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Year:

1952

Language:

english

File:

PDF, 401 KB

english, 1952

21

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C22. ASTHMA THERAPY - Depletion Of Airway Eosinophils By Benralizumab An Anti-IL5 Receptor Alpha Monoclonal Antibody

Gossage, David L., Laviolette, Michel, Gauvreau, Gail M., Leigh, Richard, Kolbeck, Roland, Wu, Yanping, Richman, Laura, Molfino, Nestor A.

Year:

2012

Language:

english

File:

PDF, 25 KB

english, 2012

22

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] A34. LUNG INJURY: MECHANISM AND INTERVENTIONS - Role Of IL-1 In Cigarette Smoke-Induced Acute Airway Inflammation

StÃ¤mpfli, Martin R., Bauer, Carla M., Nikota, James K., Zavitz, Caleb C., Davis, Nicola H.E., Coyle, Anthony J., Sleeman, Matthew A., Finch, Donna K., Kolbeck, Roland, Humbles, Alison A., Botelho, Fe

Year:

2010

File:

PDF, 16 KB

2010

23

Novel targeted therapies for eosinophilic disorders

Wechsler, Michael E., Fulkerson, Patricia C., Bochner, Bruce S., Gauvreau, Gail M., Gleich, Gerald J., Henkel, Tim, Kolbeck, Roland, Mathur, Sameer K., Ortega, Hector, Patel, Jatin, Prussin, Calman, R

Journal:

Journal of Allergy and Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 231 KB

english, 2012

24

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

Fernando M Botelho, Jake K Nikota, Carla MT Bauer, Mathieu C Morissette, Yoichiro Iwakura, Roland Kolbeck, Donna Finch, Alison A Humbles, Martin R Stämpfli

Journal:

Respiratory Research

Year:

2012

Language:

english

File:

PDF, 546 KB

english, 2012

25

Residents and fellows in radiology Annual Memorial Award competition

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Academic Radiology

Year:

1998

Language:

english

File:

PDF, 1.20 MB

english, 1998

26

Plasmacytoid dendritic cells in autoimmunity

Panda, Santosh K, Kolbeck, Roland, Sanjuan, Miguel A

Journal:

Current Opinion in Immunology

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

27

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

Panda, Santosh K., Facchinetti, Valeria, Voynova, Elisaveta, Hanabuchi, Shino, Karnell, Jodi L., Hanna, Richard N., Kolbeck, Roland, Sanjuan, Miguel A., Ettinger, Rachel, Liu, Yong-Jun

Journal:

The Journal of clinical investigation

Year:

2018

Language:

english

File:

PDF, 10.70 MB

english, 2018

28

Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

Karnell, Jodi L., Rieder, Sadiye Amcaoglu, Ettinger, Rachel, Kolbeck, Roland

Journal:

Advanced Drug Delivery Reviews

Year:

2018

Language:

english

File:

PDF, 5.85 MB

english, 2018

29

Production and characterization of recombinant mouse neurotrophin-3

Rudolf GÖTZ, Roland KOLBECK, Friedrich LOTTSPEICH, Yves-Alain BARDE

Journal:

Year:

1992

Language:

english

File:

PDF, 518 KB

english, 1992

30

Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

Séverine Létuvé, Alexander Kozhich, Alison Humbles, Yambasu Brewah, Marie-Christine Dombret, Martine Grandsaigne, Homa Adle, Roland Kolbeck, Michel Aubier, Anthony J. Coyle, Marina Pretolani

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1015 KB

english, 2010

31

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

Botelho, Fernando, Dubey, Anisha, Ayaub, Ehab A., Park, Rex, Yip, Ashley, Humbles, Allison, Kolbeck, Roland, Richards, Carl D., Gladue, Ronald

Journal:

Mediators of Inflammation

Year:

2020

File:

PDF, 3.62 MB

2020

32

Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands

Stephens, Geoffrey L., Wang, Qun, Swerdlow, Bonnie, Bhat, Geetha, Kolbeck, Roland, Fung, Michael

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 927 KB

english, 2013

33

SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus

Smith, Michael A., Henault, Jill, Karnell, Jodi L., Parker, Melissa L., Riggs, Jeffrey M., Sinibaldi, Dominic, Taylor, Devon K., Ettinger, Rachel, Grant, Ethan P., Sanjuan, Miguel A., Kolbeck, Roland,

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

34

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

Schnell, Lisa, Schneider, Regula, Kolbeck, Roland, Barde, Yves-Alain, Schwab, Martin E.

Journal:

Year:

1994

File:

PDF, 526 KB

1994

35

Distinct roles of the complement C5a receptors C5aR and C5L2 in bacterial and bacterial component-induced inflammation in human whole blood

Ling-Ling An, Roland Kolbeck, Michael Fung

Journal:

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

36

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B36. AIRWAY IMMUNE MECHANISMS AND INFLAMMATION: ANIMAL MODELS - The Epithelial-Derived Signals TSLP, IL-25 And IL-33 Converge On OX40L To Elicit House Dust Mite-Induced Allergic Airway Inflammation In Mice

Llop-Guevara, Alba, Chu, Derek K., In, Tracy S., Moore, Cheryl Lynn, Boudreau, Jeanette, Walker, Tina D., Goncharova, Susanna, Comeau, Michael, Budelsky, Alison, Kolbeck, Roland, Humbles, Alison A., J

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

37

B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

Rieder, Sadiye Amcaoglu, Wang, Jingya, White, Natalie, Qadri, Ariful, Menard, Catherine, Stephens, Geoffrey, Karnell, Jodi L., Rudd, Christopher E., Kolbeck, Roland

Journal:

Cellular & Molecular Immunology

Year:

2020

Language:

english

File:

PDF, 1.26 MB

english, 2020

38

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] D31. ANIMAL MODELS OF AIRWAY INFLAMMATION - Influenza-A Infection Alters The Immune Responsiveness To House Dust Mite In Neonatal Mice And Accelerates The Onset Of Airway Remodeling

Al-Garawi, Amal, Walker, Tina, Fattouh, Ramzi, Goncharova, Susanna, Botelho, Fernando, Humbles, Alison A., Kolbeck, Roland, Coyle, Anthony J., Jordana, Manel

Year:

2010

File:

PDF, 18 KB

2010

39

Noncanonical autophagy: one small step for LC3, one giant leap for immunity

Mehta, Payal, Henault, Jill, Kolbeck, Roland, Sanjuan, Miguel A

Journal:

Current Opinion in Immunology

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

40

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

Henault, Jill, Martinez, Jennifer, Riggs, Jeffrey M., Tian, Jane, Mehta, Payal, Clarke, Lorraine, Sasai, Miwa, Latz, Eicke, Brinkmann, Melanie M., Iwasaki, Akiko, Coyle, Anthony J., Kolbeck, Roland, G

Journal:

Year:

2012

Language:

english

File:

PDF, 1.69 MB

english, 2012

41

Development of an anti-C5/C5a antibody therapeutic that inhibits inflammatory responses via C5aR and C5L2 while maintaining MAC-dependent bactericidal functions

Ling-Ling An, Caroline Colley, Claire Dobson, Joanne Brennan, Kaiyong Yang, Jingying Zha, Paul Warrener, Bret Sellman, Roland Kolbeck, Michael Fung

Journal:

Year:

2012

Language:

english

File:

PDF, 69 KB

english, 2012

42

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

Busse, William W., Katial, Rohit, Gossage, David, Sari, Suha, Wang, Bing, Kolbeck, Roland, Coyle, Anthony J., Koike, Masamichi, Spitalny, George L., Kiener, Peter A., Geba, Gregory P., Molfino, Nestor

Journal:

Journal of Allergy and Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 530 KB

english, 2010

43

Neurotrophin Release by Neurotrophins: Implications for Activity-Dependent Neuronal Plasticity

Marco Canossa, Oliver Griesbeck, Benedikt Berninger, Gabriele Campana, Roland Kolbeck and Hans Thoenen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.53 MB

english, 1997

44

Neurotrophin-3 Induced by Tri-Iodothyronine in Cerebellar Granule Cells Promotes Purkinje Cell Differentiation

Dan Lindholm, Eero Castrén, Pantelis Tsoulfas, Roland Kolbeck, Maria da Penha Berzaghi, Axel Leingärtner, Carl-Philipp Heisenberg, Lino Tesarollo, Luis F. Parada and Hans Thoenen

Journal:

The Journal of Cell Biology

Year:

1993

Language:

english

File:

PDF, 2.75 MB

english, 1993

45

Complement C5a potentiates uric acid crystal-induced IL-1β production

An, Ling-Ling, Mehta, Payal, Xu, Linda, Turman, Sean, Reimer, Thornik, Naiman, Brian, Connor, Jane, Sanjuan, Miguel, Kolbeck, Roland, Fung, Michael

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 989 KB

english, 2014

46

Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus

Rahman, Saifur, Sagar, Divya, Hanna, Richard N, Lightfoot, Yaima L, Mistry, Pragnesh, Smith, Carolyne K, Manna, Zerai, Hasni, Sarfaraz, Siegel, Richard M, Sanjuan, Miguel A, Kolbeck, Roland, Kaplan, M

Journal:

Annals of the Rheumatic Diseases

Year:

2019

Language:

english

File:

PDF, 2.49 MB

english, 2019

47

[Lupus Foundation of America 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5â8, 2019, Abstract Presentations - ()] Abstracts - 45âCD11c-hi T-bet+ B cells contribute to the pathogenesis of SLE through generation of autoreactive plasma cells

Wang, Shu, Maul, Robert W, Kumar, Varsha, Wang, Jingya, Karnell, Jodi L, Hasni, Sarfaraz, Siegel, Richard M, Cancro, Michael P, Kolbeck, Roland, Gearhart, Patricia J, Ettinger, Rachel

Year:

2019

File:

PDF, 231 KB

2019

48

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A32. SMOKE-RELATED ALTERATIONS IN LUNG BIOLOGY - Importance Of IL-1 Receptor 1 In The Autoimmune Response Elicited By Cigarette Smoke

Morissette, Mathieu C., Jobse, Brian N., Nikota, Jake K., Shen, Pamela, Kolbeck, Roland, Finch, Donna, Humbles, Alison A., Stampfli, Martin R.

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

49

IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis

Wilson, Todd M., Maric, Irina, Shukla, Juhi, Brown, Margaret, Santos, Carlo, Simakova, Olga, Khoury, Paneez, Fay, Michael P., Kozhich, Alexander, Kolbeck, Roland, Metcalfe, Dean D., Klion, Amy D.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 596 KB

english, 2011

50

Relative Contribution of Endogenous Neurotrophins in Hippocampal Long-Term Potentiation

Chen, Guiquan, Kolbeck, Roland, Barde, Yves-Alain, Bonhoeffer, Tobias, Kossel, Albrecht

Journal:

Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

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